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Tuesday
May292012

Obese women at increased risk of developing rheumatoid arthritis

20 percent higher chance of getting the autoimmune disease, study showsObese women may have an increased risk of developing rheumatoid arthritis — adding one more chronic illness to the list of ills brought on by extra pounds.

Women with rheumatoid arthritis are already more prone to heart attacks than the general population because of their autoimmune disease.

The study by the Mayo Clinic, which was published in the April edition of Arthritis Care & Research, found the risk of getting rheumatoid arthritis was about 20 percent more for women who were overweight.

The researchers followed 813 patients with rheumatoid arthritis and the same number of controls. They also studied other patient data from 1980 to 2007 and found that from 1985 to 2007 the incidence of rheumatoid arthritis rose 9.2 percent per 100,000 women. Obesity accounted for 52.2 percent of the increase.

Rheumatoid arthritis is an inflammatory disease that causes pain, swelling and stiffness in the joints and surrounding tissues. About 1.3 million people in the United States have the disease, which occurs in two to three times as many women as men, according to the National Institutes of Health.

Obesity is blamed for myriad health problems, including diabeteshigh blood pressure, stroke, some forms of cancersleep apneagallbladder disease and osteoarthritis. Rheumatoid arthritis will likely be added to the list.

"We'll be paying more attention to their weight," said Dr. Nadera Sweiss, director of rheumatology clinical research and the Cold Hand Clinic at the University of Illinois Hospital and Health Sciences System.

"We (already) try to counsel patients with rheumatoid arthritis about other risk factors forheart disease like smoking, high blood pressure, high cholesterol," Sweiss said.

Sweiss pointed out that an article in the May edition of the Annals of the Rheumatic Diseases showed a link between obesity and psoriatic arthritis, a type of arthritis that occurs in the joints.

Dr. James Grober, a rheumatologist with NorthShore University HealthSystem in Evanston, said there had been growing evidence that fat tissue was a source of inflammatory mediators. He said the disease was likely caused by a combination of genetic susceptibility and predisposition and some other factor. The Mayo study mentions that rheumatoid arthritis may be associated with chronic inflammation, vitamin D deficiency and sexhormones, as well as risk factors like smoking and oral contraceptives.

"I think I was surprised at the magnitude of the apparent influence of obesity on the risk of rheumatoid arthritis," Grober said.

Dr. Eric Matteson, who wrote the study with Cynthia Crowson, Dr. John Davis III and Dr. Sherine Gabriel, said they had wanted to find the reasons behind an increase in rheumatoid arthritis in the past two decades. They realized obesity had also increased in that time period.

"The biological connection is we know that fat cells produce inflammatory proteins and they're active in inflammation," said Matteson, who chairs the rheumatology department at the Mayo Clinic.

"Your risk is still not huge of getting rheumatoid arthritis, but it's increased by that much more if you are overweight, so that's not trivial when you think of how many people in this country have rheumatoid arthritis," he said.

More people with rheumatoid arthritis could place a further burden on underserved individuals, as well as the country's health system, according to Sweiss, who sees many patients with the disease who are poor, smoke cigarettes, and don't have healthy diets or exercise regularly. She noted that, once the illness becomes severe, the medications needed — like Orencia or Humira — cost several thousand dollars monthly.

"This has a huge economical impact, especially since we're living in a time of economic crisis and it may be hard for patients to afford medications," Sweiss said.

Via:  Chicago Tribune

Tuesday
May292012

The Political Economy of the Obesity Epidemic

A few weeks ago I was called upon to debate the idea of taxing big, high calorie soft drinks to help offset the high health costs of the American obesity epidemic. Since then, I been dipping a toe into this literature and finding it quite interesting. Given partisan gridlock, money in politics, and filibuster abuse, nothing's easy in public policy these days. And when you start regulating food policy, you bump into the personal freedom/responsibility issues that always loom large in our debates.

But at least in terms of the economic arguments, there's low hanging (and highly nutritious) fruit in terms of negative externalities, Pigouvian taxation, and "do no harm" legislation.

Before I get to those points, however, a quick review of some relevant facts of the case. Here's an excellent new infographic from the Institute of Medicine. While there's predictable controversy over what to do about this, there's little disagreement over a) the facts, and b) their negative implications for both health and the costs to society (see also this fact sheet from the CDC). Policy-wise, this gives this epidemic a leg-up over, say, global warming, where we still have to argue the science with deniers.

- 1/3 of kids and 2/3 of adults are overweight or obese (in each case, about half of those shares are obese, so about 1/3 of adults are obese and about 17% of kids).

- Trends over the last decade have drifted up, mostly among men and boys.

- CDC: "No state has met the nation's goal to lower obesity prevalence to 15%. The number of states with an obesity prevalence of 30% or more has increased to 12 states in 2010. In 2009, nine states had obesity rates of 30% or more. In 2000, no state had an obesity prevalence of 30% or more."

- Obesity rates are correlated with income, poverty, and education level but that's not the whole story -- there's variation within all those groups. The figure at the end of this post shows the correlation between obesity and poverty rates by state -- the regression line is significant and has a slope of about 0.5, implying a one-percentage point increase in poverty is associated with about a half-a-point higher obesity rates, but the poverty variable by itself only explains about a quarter of the variation across the states. By the way, the outlier there in upper right-hand corner is Mississippi.

Now, to the economics.

Here at On The Economy, we're a bit obsessed with externalties and that's what makes this obesity/overweight problem such a compelling area of inquiry. The weight epidemic generates very significant and widespread costs that spillover to the rest of society. About 20% of health spending is on related problems, and they tend to be chronic, like hypertension and type-2 diabetes -- and in our health care system, chronic = expensive.

There's also lost productivity at work along with lots of other less recognizable costs (air travel actually costs more now because heavier flight loads!).

So, as long as everyone's paying the price -- through higher health insurance premiums and taxes to support the public side of the health system -- there's an undeniable rationale for corrective public policy. The question is, what's the best policy response?

I see two venues here, call them micro and macro.

On the micro side, a Pigouvian tax is a tax on an activity that causes a negative externality, like taxing a polluter. In prepping for my soft drinks debate, I found this brief by a couple of my CBPP colleagues very helpful. The line of argument goes like this:

- The increased caloric content of sugary drinks has contributed to the epidemic;

- The epidemic is a significant contributor to the increase in health costs;

- There's a large price elasticity in play here.

This last point is the crucial one from the policy perspective. According the brief, a 10% increase in cost will reduce consumption by about 8%. Now, that's but one study but there have been others with similar findings, and the tobacco literature also supports this response. Thankfully, consumers of big, fat soft drinks are pretty price sensitive.

I would strongly advocate that any proceeds from such a tax be used for health care, overweight prevention programs, and my personal favorite policy idea in this area: provision of active, fun, safe, and very cool play spaces for kids, with a big emphasis on places where such play spaces don't currently exist. There's good research, by the way, correlating the location of such spaces to lower obesity rates among kids.*

My advocacy for using the tax revenue in these ways is also based on making a simple, common-sense connection between the epidemic, the tax, and the solution. I believe there would be a lot more support for placing a tax on stuff that's partially responsible for this problem if we're using the proceeds to fix the problem, particularly if we do so in a way that improves neighborhoods.

On the macro side, there's this interesting interview I stumbled on the other day. This scientist who studies the epidemic is asked what, according to his research, caused it:

The epidemic was caused by the overproduction of food in the United States.

 

Beginning in the 1970s, there was a change in national agricultural policy. Instead of the government paying farmers not to engage in full production, as was the practice, they were encouraged to grow as much food as they could. At the same time, technological changes and the "green revolution" made our farms much more productive. The price of food plummeted, while the number of calories available to the average American grew by about 1,000 a day.

 

Well, what do people do when there is extra food around? They eat it! This, of course, is a tremendously controversial idea. However, the model shows that increase in food more than explains the increase in weight.

Of course, here again, there's a lot more to it. It's not just food production, it's the type of food, its fat and sugar content in particular, and the fact that the cost structure very much supports cheap, unhealthy calories relative to the stuff that's much better for us.

But it's hard to imagine we'll solve our weight epidemic until we deal with the fact that public policy is subsidizing the production of the food that's causing it. We can have good arguments about whether should implement measures like new Pigouvian taxes that would help solve obesity -- we shouldn't have to argue to hard about getting rid of the wasteful, harmful spending that's making it worse.

Finally, what about personal responsibility? That's the conservative response to all of this -- the idea that your weight is your problem and not an issue for the public policy.

Obesity and Poverty Rates, by State, 2010I understand the impulse here -- the idea that no one wants the government getting involved in the menu. But that's where the externality comes in. As long as something like this is solely a problem in the personal realm, where prices fully reflect the risk factors, then I'd agree -- government stay out! The minute it becomes a cost to the rest of us, that argument is toast (whole-wheat toast, in this case). Those massive soft drinks are socially underpriced, and that's a problem for all of us.

In this regard, there's another policy idea that is increasingly bandied about here: the idea that we can "internalize the externality" by simply charging overweight individuals themselves for the costs they're imposing on the rest of us. For example, you could ratchet up insurance costs for overweight people, or provide insurance discounts for those engaging in weight loss activities.

A lot of this latter stuff goes on already and there's more to come in the Affordable Care Act -- I'll post on it soon. But there are problems here -- what about low-income, overweight people who can't afford the higher premiums? What about the uninsured? I'm all for an "all-of-the-above" approach to solving the obesity epidemic, and these targeted ideas should be part of it, but they won't work by themselves.

More to come as I continue to delve into this research, including info on some neat local programs that are helping. But the larger point is that, assuming we someday get back to making useful national policy, here's an area where we could make a big positive difference both to people's lives and to society's balance sheet.

Sources: Poverty Rates, Census Bureau (avg for 2009-10); State Obesity Rates, CDC

Via:  Huffington Post

 

 

Tuesday
May292012

Obesity program helping children

The Bradenton-Sarasota Chapter of the Links Inc. recently completed a two-year childhood obesity prevention health initiative with students at Emma E. Booker Elementary School.

The program involved more than 60 students and encouraged them to maintain a healthier lifestyle through increased awareness of healthy eating, reading food labels for nutrient values, the benefits of routinely practicing physical activity and how to help their parents plan, shop for and prepare healthy meals.

The six-week "Can You Imagine Me?" curriculum was designed by the Morehouse School of Medicine in collaboration with the Links Inc. and sponsored by the W.K. Kellogg Foundation and General Mills Inc.

The pilot culminated with a program to acknowledge and celebrate what the students learned about healthy eating and physical activity.

At the end of the program, parents, guardians, family members and friends were invited to see the students demonstrate what they learned. The event included singing, dancing and eating healthy foods and desserts. Each student received a backpack with nutritional information, activity gifts and a certificate of completion.

The program was underwritten by a grant from the Florida Blue Cross, Blue Shield of Tampa.

The local Links chapter plans to collaborate with other community partners to extend the childhood obesity prevention program to after-school programs in Sarasota and Manatee counties.

Via:  Herald Tribune

Monday
May282012

Supermarket Counseling Could Improve Your Shopping Choices

The grocery store can be a confusing place when you are trying to choose healthy foods. Though nearly all foods have a Nutrition Facts label, not everyone knows how to read or interpret the label correctly. Some food packages have health claims printed on them, and some stores provide indicators that certain foods are good for you. But it can get to be a bit confusing unless you have a degree in nutrition.

Researchers at the University of Arizona College of Medicine and Arizona State University set out to determine if providing in-store nutrition counseling could make a difference in the foods shoppers chose. A supermarket chain offered a packaged EatSmart program created by a registered dietitian chosen for the study.

The foods people purchase are indicative of their dietary intake so education and information can have a long lasting impact on the diets and health of individuals and families.

The program includes colorful nutrition shelf tags placed under items using recommendations from the American Heart Association: "healthier option," "hearthealthy," "calcium rich, "immune booster," or "low sodium." In all, each store had about 600 shelf tags. EatSmart educational materials were also available in the stores.

Shoppers were recruited onsite. Half of the 153 participants shopped using only the store labels and had no other nutrition education. The other half of the shoppers had a 10-minute face-to-face session with a nutrition educator that focused on better understanding of two of the labels, "heart healthy" and"immune booster," before they shopped.

For the purposes of the EatSmart program, "heart healthy" foods include those that are low in total fat, saturated fat, and trans fats. All fruits and vegetables, and particularly the dark green and bright yellow, orange, and red produce, are considered "immune boosters."

After the participants completed their shopping, researchers analyzed each grocery cart to determine the fat content and the amount and color of the fruits and vegetables purchased. Those who received the face-to-face intervention purchased more servings of whole fruit and dark green and bright yellow vegetables compared to the group who received no nutrition education. There was no difference in the fat content of the carts between the two groups.

The foods people purchase are indicative of their dietary intake so education and information can have a long lasting impact on the diets and health of individuals and families. The value of face-to-face nutrition education by a registered dietitian at the point of purchase (the grocery store) may be a service grocery store merchants (or public health officials) should consider offering.

The study was published in the May issue of the Journal of Nutrition Education and Behavior.

Via:  The Atlantic

Wednesday
May232012

Fungicide Study Links Chemical To Autism, Obesity, Stress And Anxiety

Being exposed to Fungicide when pregnant could leave your children, grand children and even great grandchildren with an increasing amount of anxiety, stress, autism and obesity.

The study published in the Proceedings of the National Academy of Sciences studies pregnant rats and found that the conditions mentioned above increased with exposure to fungicide during pregnancy.

According to lead author David Crews of the University of Texas:

“We are now in the third human generation since the start of the chemical revolution, since humans have been exposed to these kinds of toxins. There is no doubt that we have been seeing real increases in mental disorders like autism and bipolar disorder.”

To conduct their study researchers exposed pregnant rats to vinclozolin, a commonly used fungicide for fruits and vegetables which is known to disrupt hormones. Researchers used a “higher than expected” amount of the chemical when compared to what is found in the environment. Researchers were able to use a higher level of the substance because they were not attempting to determine the risk for humans but rather understand the phenomena caused by exposure.

After exposing up to three generations of male rates they found that third generation rats were more stressed in stressful situations of physical restraint during adolescence. The rats with a history of exposure to fungicide were also heavier and had higher testosterone levels.

According to a Google AFP wired:

“They were also more anxious, more sensitive to stress, and showed greater activity in stress-related regions of the brain than descendants of unexposed rats.”

In terms of examining the possibility of autism related risk the exposed rats showed less interesting in new individuals and environments.

Researchers believe that high levels of exposure ultimately changed the sperm and eggs genetic makeup which less to stress responses in future generations of rats.

While Vinclozolin began wide spread use in the 1980s to prevent crop rot it began to decline after researchers discovered its effects on male hormones and sexual development.

Via:  The Inquisitr